1

Lihua Xu, Guihua Tong, Qiaoli Song, Chunyu Zhu, Hongling Zhang, Jinjin Shi, Zhenzhong Zhang

Enhanced Intracellular Ca²⁺ Nanogenerator for Tumor-Specific Synergistic Therapy viaDisruption of Mitochondrial Ca²⁺ Homeostasis and Photothermal Therapy

13.70

ACS Nano

2018, 12(7): 6806-6818

2

Binghua   Wang, Jingyi An,   Huifang   Zhang, Shudong   Zhang, Huijuan   Zhang, Lei Wang,   Hongling   Zhang, Zhenzhong   Zhang

Personalized Cancer Immunotherapy via Transporting   Endogenous Tumor Antigens to Lymph Nodes Mediated by Nano Fe₃O₄

10.22

Small

2018, 14(38): 1801372

3

Jinjin Shi, Wei Liu, Yu Fu, Na Yin, Hongling Zhang,   Junbiao Chang,

Zhenzhong Zhang

“US-detonated nano bombs” facilitate targeting   treatment of resistant breast cancer

7.786

Journal of Controlled Release

2018, 274: 9–23

4

Qianhua Feng, Yuzhen Li, Xuemei Yang, Wanxia Zhang,

Yongwei Hao, Hongling Zhang, Lin Hou, Zhenzhong Zhang

Hypoxia-specific therapeutic agents delivery   nanotheranostics: A sequential strategy for ultrasound mediated on-demand tritherapies   and imaging of cancer

7.786

Journal of Controlled Release

2018，275：192–200

5

Lei Wang,   Yujie Hu,   Yongwei Hao,   Li Li,   Cuixia Zheng,   Hongjuan Zhao,   Mengya Niu,   Zhenzhong Zhang, Yun Zhang

Tumor-targeting core-shell structured nanoparticles   for drug procedural controlled release and cancer sonodynamic combined   therapy

7.786

Journal of Controlled Release

2018, 286: 74-84

6

Hou Lin, Liu Qi, Shen Limei, Liu Yun, Zhang Xueqiong, Chen Fengqian,   Huang Leaf.

Nano-delivery of fraxinellone remodels tumor microenvironment and   facilitates therapeutic vaccination in desmoplastic melanoma.

8.537

Theranostics

2018;14:3781-3796.

7

Hongjuan   Zhao, Li Li, Junli Zhang, Cuixia Zheng, Kaili Ding, Huifang Xiao, Lei Wang, Zhenzhong Zhang

C–C Chemokine Ligand 2 (CCL2) Recruits   Macrophage-Membrane-Camouflaged Hollow Bismuth Selenide Nanoparticles To   Facilitate Photothermal Sensitivity and Inhibit Lung Metastasis of Breast   Cancer

8.097

ACS Appl Mater Interfaces

2018,10(37): 31124-31135

8

Hou Lin, Zhang Yinling, Yang Xuemei, Tian Chunyu, Yan Yingshan, Zhang   Hongling, Shi Jinjin, Zhang Huijuan, Zhang Zhenzhong.

Intracellular NO-Generator Based on Enzyme Trigger for Localized   Tumor-Cytoplasm Rapid Drug Release and Synergetic Cancer Therapy.

8.097

ACS Appl Mater Interfaces

doi: 10.1021/acsami.8b17750.

9

Hou Lin, Zheng Yazhen, Wang Yongchao, Hu Yurong, Shi Jinjin, Liu Qi,   Zhang Huijuan, Zhang Zhenzhong.

Self-Regulated Carboxyphenylboronic Acid-Modified Mesoporous Silica   Nanoparticles with "Touch Switch" Releasing Property for Insulin   Delivery.

8.097

ACS Appl Mater Interfaces

2018, 26: 21927-21938

10

Qianhua Feng, Wanxia Zhang, Xuemei Yang, Yuzhen Li,   Yongwei Hao, Hongling Zhang,

Lin Hou, Zhenzhong Zhang

pH/Ultrasound Dual-Responsive Gas Generator for Ultrasound   Imaging-Guided Therapeutic Inertial Cavitation and Sonodynamic Therapy

5.11

Adv. Healthcare Mater

2017, 1700957

11

Lei Wang ,   Mengya Niu ,   Cuixia   Zheng , Hongjuan   Zhao , Xiuxiu Niu ,   Li Li,   Yujie Hu ,   Yingjie   Zhang , Jinjin Shi ,   Zhenzhong   Zhang

A Core–Shell Nanoplatform for Synergistic Enhanced   Sonodynamic Therapy of Hypoxic Tumor via Cascaded Strategy

5.11

Adv. Healthcare Mater

2018, 1800819

12

Bin Du, Shaona Jia, Qinghui Wang, Xiaoyu Ding, Ying Liu, Hanchun   Yaoand Jie Zhou

A self-targeting, dual ROS/pH- responsive apoferritin nanocage for   spatiotemporally controlled drug delivery to breast cancer

5.738

Biomacromolecules

2018, 19:1026-1036

13

Junli   Zhang, Jinjin Shi, Wei Liu, Kaixiang Zhang, Hongjuan Zhao, Hongling Zhang,

Zhenzhong Zhang

A simple, specific and “on-off” type MUC1 fluorescence   aptasensor based on exosomes for detection of breast cancer

5.401

Sensors and Actuators B: Chemical

2018,276：552-559

14

Jie Zhou, Weiran Ye, Lingchang Meng, Chong Sun, Shanshan Chen, Pei   Luo

Preparation and application of a new biochromatography based on small   origami assembled PPAR

5.667

Sensors and Actuators B

2018; 261: 581-586

15

Yao Hanchun, Zhao Weiwei, Zhang Suge, Guo Xiaofang, Li Ying, Du Bin

Dual-functional carbon dot-labeled heavy-chain ferritin for   self-targeting bio-imaging and chemo-photodynamic therapy

4.776

Journal of Materials Chemistry B

2018, 6: 3107-3115

16

Shengnan   Huang, Ying Liu, Xin Xu, Mengfei Ji, Yuanmin Li, Chengjun Song, Shaofeng   Duan, Yurong Hu

Triple   therapy of hepatocellular carcinoma with microRNA-122 and doxorubicin   co-loaded functionalized gold nanocages

4.776

Journal of Materials Chemistry B

2018, 6,   2217

17

Huijuan Zhang, Jianjiao Chen, Xing   Zhu,Yanping Ren， Fang   Cao, Ling Zhu, Lin Hou, Hongling Zhang， Zhenzhong Zhang

Ultrasound induced phase-transition and invisible nanobomb for imaging-guided tumorsonodynamic therapy

4.776

Journal of Materials Chemistry B

2018, 6(38): 6108-6121

18

Mengfei Ji, Xiaojing Qiu, lin hou, shengnan huang,   Yuanmin li, Yang liushaofeng Duan, Yurong hu*

construction and application of a liver   cancer-targeting drug delivery system based on core–shell gold nanocages

4.37

International   journal of nanomedicne

2018;13:1773-1789

19

Jie Zhou, Lingchang Meng, Chong Sun, Weiran Ye, Chengqun Chen,Bin Du

A“protective umbrella”nanoplatform for loading ICG and   multi-modal imaging-guided phototherapy

5.72

Nanomedicine: Nanotechnology, Biology and Medicine

2018,14:289-301

20

Huijuan Zhang; Xiaoge Zhang; Xing Zhu; Jianjiao Chen;   Qianqian Chen; Hongling Zhang; Lin Hou; Zhenzhong Zhang

NIR light-induced tumor phototherapy using   photo-stable ICG delivery

system based on inorganic hybrid

5.72

Nanomedicine: Nanotechnology, Biology and Medicine

2018, 14: 73-84

21

Nan Zhang, Jiangnan Zhang, Pei Wang, Xinyang Liu, Pengchao Huo, Yue   Xu, Wenjie Chen, Hongying Xu, Qingfeng Tian

Investigation of an antitumor drug-delivery system based on anti-HER2   antibody-conjugated BSA nanoparticles

1.869

Anti-Cancer Drugs

2018, 29:307–322

22

Qinghui Wang, Xiaoyu Ding, Yuhui Wang, Qian Du, Tianguo Xu, Bin Du, Hanchun   Yao

The ratiometric fluorescence nanoparticle based on SiRB for pH   detection of tumor

3.466

European Journal of Pharmaceutical Sciences

2018,118:32-39

23

Bin Du, Xiaosa Yan, Xiaoyu Ding, Qinghui Wang, Qian Du, Tianguo Xu,   Guopeng Shen, Hanchun Yao and Jie Zhou

Oxygen self-production red blood cell carrier system for mri mediated   cancer therapy:ferryl-hb, sonodynamic, and chemical therapy

4.432

ACS Biomater. Sci. Eng.

2018, 4:4132-4143

24

Jie Zhou, Lingchang Meng, Weiran Ye, Qiaolei Wang, Shizhen Geng, Chong   Sun

A sensitive detection assay based on signal amplification technology for   Alzheimer's disease's early biomarker in exosome

5.123

Analytica Chimica Acta

2018; 1022: 124-130

25

Zhi Li, Junya Zhang, Xiaonan Guo, Xinhong Guo, Zhenzhong   Zhang

Multi-functional magnetic nanoparticles

as an effective drug carrier for the

controlled anti-tumor treatment

2.31

Journal of Biomaterials Applications

2018, 32(7): 967–976

26

Zhi Li,   Junya Zhang,   Xiao Li, Xinhong Guo   , Zhenzhong   Zhang

Preparation and Evaluation of Multifunctional Autofluorescent   Magnetic Nanoparticle–Based Drug Delivery Systems Against Mammary Cancer

3.07

Journal of pharmaceutical sciences

2018, 107(10): 2694-2701

27

Hongjuan   Zhao, Li Li, Cuixia Zheng, Yongwei   Hao, Mengya Liu, Yujie Hu, Junbiao Chang, Zhenzhong Zhang, Lei   Wang

An intelligent dual stimuli-responsive photosensitizer delivery system with O₂-supplying for   efficient photodynamic therapy

3.997

Colloids and Surfaces B: Biointerfaces

2018,167:299-309

28

JunXia   Zhang ,JiaoMei Guo ,TingTing   Zhang ,HongJun Lin ,NaiSong Qi ,ZhenGuo Li ,   JiChun Zhou ,ZhenZhong   Zhang

Antiproliferative Phenothiazine Hybrids as Novel Apoptosis Inducers against MCF-7 Breast   Cancer

3.268

Molecules

2018, 23(6): 1288

29

Weiping   Wang, Shengnan Huang, Jinxiu Yuan, Xin Xu, Huili Li, Zhanwei Lv, Wei Yu, Shaofeng   Duan, Yurong Hu

Reverse   Multidrug Resistance in Human HepG2/ADR by Anti-miR-21

Combined   with Hyperthermia Mediated by Functionalized Gold Nanocages

4.556

Mol.   Pharmaceutics

2018,   15, 3767−3776

30

Pengchao   Sun, Nan Zhang, Yafang Tang, Yanan Yang, Jie Zhou, Yongxing   Zhao

Site-specific   anchoring aptamer C2NP on DNA origami nanostructures for cancer treatment

2.936

RSC Adv

2018 ,   8:26300-26308

31

Nan   Zhang, Chunyu Xu, Na Li, Shasha Zhang, Lingling Fu, Xiao Fu, Haiying Hua,   Xianhui Zeng, Yongxing Zhao

Folate receptor-targeted   mixed polysialic acid micelles for combating rheumatoid arthritis: in vitro   and in vivo evaluation

3.095

Drug   Deliv

2018, 25(1):1182-1191

32

贾欣，冯倩华，张超锋，王蕾，王希，杜娟

透明质酸修饰的中空介孔硫化铜负载阿霉素载药体系在乳腺癌模型裸鼠体内的分布行为及抗肿瘤效果观察

郑州大学学报（医学版）

2018,53（6）：738-743

33

张振中，张慧娟

具有微能量响应特征的无机纳米递药系统研究进展

郑州大学学报(医学版)

2018,   53(5): 541-547