Which is Better for Nanomedicines: Nanocatalysts or Single-Atom Catalysts?
【作者】Mengyang Zhao*, Nan Zhang*, Ruigeng Yang, Deliang Chen*#, and Yongxing*#Zhao
【期刊名】ADVANCED HEALTHCARE MATERIALS
【影响因子】2020年: 9.933
【作者单位】State Key Laboratory of Esophageal Cancer Prevention and Treatment Department of Pharmaceutics School of Pharmaceutical Sciences Zhengzhou University No. 100 Kexue Ave, Zhengzhou 450001, P. R. China
【年,卷(期):页码】2021 Apr;10(8): 2001897
【关键词】nanocatalysts, single-atom catalysts, nanomedicine, cancer treatment, anti-bacterial treatment, anti-inflammatory treatment
【摘要】With the rapid advancements in nanotechnology and materials science, numerous nanomaterials have been used as catalysts for nanomedical applications. Their design and modification according to the microenvironment of diseases have been shown to achieve effective treatment. Chemists are in pursuit of nanocatalysts that are more efficient, controllable, and less toxic by developing innovative synthetic technologies and improving existing ones. Recently, single-atom catalysts (SACs) with excellent catalytic activity and high selectivity have attracted increasing attention because of their accurate design as nanomaterials at the atomic level, thereby highlighting their potential for nanomedical applications. In this review, the recent advances in nanocatalysts and SACs are briefly summarized according to their synthesis, characterizations, catalytic mechanisms, and nanomedical applications. The opportunities and future scope for their development and the issues and challenges for their application as nanomedicine are also discussed. As far as it is known, the review is the systematic comparison of nanocatalysts and SACs, especially in the field of nanomedicine, which has promoted the development of nanocatalytic medicine.
【全文链接】
https://onlinelibrary.wiley.com/doi/10.1002/adhm.202001897