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    赵洪娟

    2022-07-15 赵洪娟  点击:[]


    郑州大学药学院直聘研究员。主要学术研究方向为药物递送系统联合肿瘤免疫治疗。曾参与国家自然科学基金面上项目、国家自然科学基金联合项目和国家自然科学基金青年项目等多项科研项目。近年来,以第一作者在国际专业高水平期刊Advanced Functional MaterialsIF 19.924)、ACS NANOIF 18.027)、Advanced Healthcare MaterialsIF 11.092)、ACS Applied Materials & InterfacesIF 10.383)等上发表相关论文5篇,申请发明专利3项。

    联系方式:zhaohongjuan@zzu.edu.cn

    工作与教育经历:

    2022.01-至今,郑州大学,药学院药物分析系,直聘研究员

    2017.09-2021.12,郑州大学,药物化学,博士

    2011.09-2015.06,郑州大学,药学,学士

    主持或参加研究项目:

    1. 国家自然科学基金委员会, 联合基金项目, U1804183, 肿瘤“主动招募”式仿生纳米“特工”对乳腺癌的治疗研究, 2019-01-01 2021-12-31, 48万元, 在研, 参与

    2. 国家自然科学基金委员会, 青年科学基金项目, 81703433, 基于表面性质智能转变、高效穿透粘液和上皮细胞屏障的口服纳米粒构建及研究, 2018-01-01 2020-12-31, 20.1万元, 结题, 参与

    3. 国家自然科学基金委员会, 面上项目, 81673021, 一种智能型“自供氧”“可视化”肿瘤靶向治疗系统的研究, 2017-01-01 2020-12-31, 58万元, 结题, 参与

    4. 河南省科学技术厅, 河南省科技攻关项目, 162102310510, 血卟啉单甲醚与吖啶黄联合增强肿瘤靶向声动力学治疗的研究, 2018-01 2019-12, 10万元, 结题, 参与

    国家发明专利:

    1. 王蕾,宋庆龄,张云,张振中,高慧,王珂,郑翠霞,赵洪娟,冯倩华,张红岭,一种基于益生菌芽孢衣壳纳米材料与益生菌组合物的制备方法及应用,2021-8-17,中国,授权,CN202011426215.1

    2. 王蕾,赵洪娟,张振中,赵倍倍,吴丽遐,一种巨噬细胞膜仿生三硒化二铋纳米粒的制备方法及应用,2019-12-6,中国,公开,CN201911242023.2

    3. 王蕾,赵洪娟,李丽,郝永伟,牛梦亚,牛秀秀,郑翠霞,胡玉洁,宋庆龄,张振中,一种基于介孔石墨相氮化碳的抗肿瘤药物载体的制备方法及其应用,2017-9-6,中国,公开,CN201710796845.X

    4. 赵洪娟,王蕾,张振中,赵倍倍,吴丽遐,一种基于细胞微囊泡的抗肿瘤疫苗的制备方法及其应用,2019-12-7,中国,公开,CN201911243245.6

    学术论文

    1. Hongjuan Zhao, Qingling Song, Cuixia Zheng, Beibei Zhao, Lixia Wu, Qianhua Feng, Zhenzhong Zhang,* and Lei Wang*. Implantable Bio-Responsive Nanoarray Enhances Post-Surgical Immunotherapy by Activating Pyroptotis and Remodeling Tumor Microenvironment. Adv Funct Mater, 2020, 2005747. SCI 一区(中科院分区),IF19.9.

    2. Hongjuan Zhao, Beibei Zhao, Lixia Wu, Huifang Xiao, Kaili Ding, Cuixia Zheng, Qingling Song, Lingling Sun, Lei Wang,* and Zhenzhong Zhang*.Amplified Cancer Immunotherapy of a Surface-Engineered Antigenic Microparticle Vaccine by Synergistically Modulating Tumor Microenvironment. ACS Nano, 2019, 13, 1255312566. SCI 一区(中科院分区),IF18.0.

    3. Hongjuan Zhao, Beibei Zhao, Li Li, Kaili Ding, Huifang Xiao, Cuixia Zheng, Lingling Sun, Zhenzhong Zhang,* and Lei Wang*Biomimetic Decoy Inhibits Tumor Growth and Lung Metastasis by Reversing the Drawbacks of Sonodynamic Therapy. Advanced Healthcare Materials, 2019, 1901335. SCI 一区(中科院分区),IF11.1.

    4. Hongjuan Zhao, Li Li, Junli Zhang, Cuixia Zheng, Kaili Ding, Huifang Xiao, Lei Wang,* and Zhenzhong Zhang*. CC Chemokine Ligand 2 (CCL2) Recruits Macrophage-Membrane Camouflaged Hollow Bismuth Selenide Nanoparticles To Facilitate Photothermal Sensitivity and Inhibit Lung Metastasis of Breast Cancer. ACS Applied Materials & Interfaces, 2018, 10, 3112431135. SCI 一区(中科院分区),IF10.4.

    5. Hongjuan Zhao, Li Li, Cuixia Zheng, Yongwei Hao, Mengya Niu, Yujie Hu, Junbiao Chang, Zhenzhong Zhang, and Lei Wang*. An intelligent dual stimuli-responsive photosensitizer delivery system with O2-supplying for efficient photodynamic therapy. Colloids and Surface B: Biointerfaces167 (2018) 299-309. SCI 二区(中科院分区),IF6.0.

    6. Qingling Song, Hongjuan Zhao, Cuixia Zheng, Ke Wang, Hui Gao, Qianhua Feng, Hongling Zhang, Zhenzhong Zhang,* Yun Zhang,* and Lei Wang*. A Bioinspired Versatile Spore Coat Nanomaterial for Oral Probiotics Delivery. Adv Funct Mater, 2021, 2104994. SCI 一区(中科院分区),IF19.9.

    7. Qingling Song, Cuixia Zheng, Jiajia Jia, Hongjuan Zhao, Qianhua Feng, Hongling Zhang, Lei Wang,* Zhenzhong Zhang,* and Yun Zhang*A Probiotic Spore-Based Oral Autonomous Nanoparticles Generator for Cancer Therapy. Advanced Materials, 2019, 31, 1903793. SCI 一区(中科院分区),IF32.1.


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