姓  名：冷瑜婷

            职  称：副教授

            地  址：郑州大学化学学院

            邮  箱：yutingleng@zzu.edu.cn

教育与科研经历

2006.09－2011.06 郑州大学 有机化学 博士

2002.09－2006.06 周口师范学院 化学 学士

2011－至今 郑州大学化学学院 讲师

2018－2020 美国哈佛大学医学院 访问学者

研究领域/方向

[1] 有机合成方法学：秉承原子经济性、低污染、低排放和高转化等绿色化学的思想要求，开展具有重要理论研究价值和应用前景的有机产品的简便合成，发展具有实际应用前景的反应合成路线。

[2] 药物化学：近红外小分子荧光探针的设计、合成及应用。

代表性论文

[1] Jingcai Wang, Yuting Leng^*, Zongqiang Hu, Yuping Pan, Shiwei Wang, Yangjie Wu^*, TEMPO-mediated cross dehydrogenative coupling aminomethylation of imidazopyridine, Tetrahedron Letters, 61, 10, 1515905, 2020.

[2] Ruonan Wang, Jingcai Wang, Qingxuan Tang, Xin Zhao, Junfeng Wang, Yuting Leng^*, Yangjie Wu^*, Junbiao Chang^*, Yusheng Wu^*, Zhaoda Zhang, Shiwei Wang, Copper(I)-catalyzed direct C-H trifluoromethylation of imidazoheterocycles with Togni’s reagent, Tetrahedron Letters, 60, 8, 586-590, 2019.

[3] Ruonan Wang, Shiwei Wang, Dayong Li, Feiyang Ye, Yuting Leng^*, Yangjie Wu^*, Junbiao Chang, Yusheng Wu, Radical ring opening reaction of pyridine fused heterocycles with IBA-N₃ catalyzed by tetra-n-butylammonium iodide, Tetrahedron, 75, 15, 2298-2305, 2019.

[4] Shuaijiang Ma, Shiwei Wang ^*, Yuting Leng^*, Qian Li, Guohua Hu. Characterization and finite element analysis of the tensile behavior of electro-spun polymer single fibers. Macro Mater Eng. 303, 3, 1700593, 2018.

[5] Yong Li, Yuting Leng^*, Junbiao Chang, Yusheng Wu, Yangjie Wu^*, Oxidative acylation of α, α-diarylallylic alcohols: synthesis of 1,2,4-triarylbutane-1,4-diones. Appl. Organomet. Chem. 32, 8, e4407, 2018.

[6] Shuaijiang Ma, Shiwei Wang ^*, Qian Li^*, Yuting Leng^*, Lianhui Wang, Guohua, Hu. A Novel Method for Preparing Poly(vinyl alcohol) Hydrogels: Preparation, Characterization, and Application. Ind Eng Chem Res. 56, 28, 7971–6, 2017.

[7] Huijie Qiao, Fan Yang, Shiwei Wang, Yangjie Wu^* , Yuting Leng^*, Palladium-catalyzed ortho-nitration of 2-arylbenzoxazoles, Tetrahedron, 71(49): 9258-9263, 2015.

[8] Gaizhi Ma, Yuting Leng^*, Huijie Qiao, Fan Yang, Shiwei Wang, Yangjie Wu^*, Generally applicable and efficient esterification of aldehydes with alcohols catalyzed by cyclopalladated ferrocenylimine, Appl. Organomet. Chem., 28, 1, 44–47, 2014.

[9] Guangwei Chen, Yuting Leng^*, Fan Yang, Shiwei Wang, Yangjie Wu^*, Palladacycle-catalyzed carbonylation of aryl iodides or bromides with aryl formats, Chin. J. Chem., 31, 12, 1488–1494, 2013.

[10] Gaizhi Ma, Yuting Leng^*, Yusheng Wu, Yangjie Wu^*, Facile synthesis of 3-arylpyridine derivatives by palladacycle-catalyzed Stille cross-coupling reaction, Tetrahedron, 69, 902-909, 2013.

[11] Yuting Leng, Fan Yang, Weiguo Zhu, Yangjie Wu^* and Xiang Li, Chlorination and ortho-acetoxylation of 2-arylbenzoxazole. Org. Biomol. Chem., 9, 5288–5296, 2011.

[12] Yuting Leng, Fan Yang, Weiguo Zhu, Dapeng Zou, Yangjie Wu^*, Ranran Cai, Facile synthesis of arylboronic esters by palladacycle-catalyzed bromination of 2-arylbenzoxazoles and subsequent borylation of the brominated products. Tetrahedron, 67, 6191-6196, 2011.

[13] Yuting Leng, Fan Yang，Yangjie Wu^*, Ke Li, Cyclopalladated Ferrocenylimine Catalyzed Chlorination of 2-Arylbenzoxazoles. Chin. J. Chem., 29, 1703 -1708, 2011.

[14] Yuting Leng, Fan Yang, Kun Wei, Yangjie Wu^*, Generally applicable and efficientoxidative Heck reaction of arylboronicacids with olefins catalyzed bycyclopalladated ferrocenylimine underbase- and ligand free conditions. Tetrahedron, 66, 1244-1248, 2010.

代表性专利

[1] 冷瑜婷, 李勇, 王市伟, 吴养洁. 一种1,4-二羰基化合物及其制备方法: 中国, 201710285065.9.2020-01-02.

主持科研项目情况

[1] 主持河有南省基础与前沿技术研究计划项目，62300410003，已结项

[2] 河南省高等学校重点项目，13A150681，已结项

[3] 校级研究生教育专项基金，已结项

[4] 指导大学生创新创业训练项目3项

[5] 主持校级教改项目