孟红敏，教授，博士生导师

邮箱: hmmeng2017@zzu.edu.cn

基本信息

孟红敏，理学博士，教授，博士生导师，河南省优秀青年基金获得者。

教育背景

2010. 9-2015. 6  湖南大学化学生物传感国家重点实验室 硕博连读 导师：张晓兵教授 谭蔚泓院士

2006. 9-2010. 6  湖南大学 化学化工学院  本科 导师：宦双燕教授

工作履历

2026.01-至今        郑州大学 教授

2020.05-2025.12      郑州大学 副教授

2017.06-2020.04      郑州大学 讲师

2015.07-2017.05    河南师范大学 讲师

社会兼职

担任Chinese Chemical Letters、Journal of Analysis Testing 青年编委

研究领域

激活型光学分子探针、仿生核酸器件

研究成果（Selected publications）

主持国家自然科学基金面上项目、国家自然科学基金青年科学基金、化学生物传感国家重点实验室开放课题、河南省自然科学基金优秀青年基金、河南省重点研发与推广专项（科技攻关）等科研项目

代表性论文：

Ø Hongzhi Sun, Di Zhao, Yating He, Hong-Min Meng,* and Zhaohui Li*, Aptamer-Based DNA Allosteric Switch for Regulation of Protein Activity, Advanced Science, 2024, 11, 2402531

Ø Yanan Wu, Yating He, Miaomiao Han, Di Zhao, Bojun Liu, Kun Yuan, Hongzhi Sun, Hong-Min Meng* and Zhaohui Li*, Dual-miRNA-Propelled Three-Dimensional DNA Walker for Highly Specific and Rapid Discrimination of Breast Cancer Cell Subtypes in Clinical Tissue Samples, CCS Chemistry, 2023, 5, 1561–1573

Ø Kun Yuan, Hong-Min Meng*, Yanan Wu, Juan Chen, Hui Xu, Lingbo Qu, Lele Li and  Zhaohui Li*, Extracellular Milieu and Membrane Receptor Dual-Driven DNA Nanorobot for Accurate in vivo Tumor Imaging, CCS Chemistry, 2022, 4, 1597–1609.

Ø Di Zhao, Aifang Zhou, Tengfei Zhang, Chen Han, Hong-Min Meng*, Yuehe Lin, Zhaohui Li,* Building high-contrast afterglow nanoprobe using semiconducting polymer nanoparticles and CuRu nanozyme for prolonged surgical navigation, Nano Today, 2025, 63, 102750

Ø Chen Han, Zhihui Jia, Chiyuan Wei, Tengfei Zhang, Rong Wang, Hong-Min Meng,* and Zhaohui Li, A Novel Afterglow Molecular Probe for Monitoring of pH and Viscosity in Infected Wounds with Two-Dimensional Signal, Analytical Chemistry, 2025, 97,10821−10829.

Ø Yanan Wu, Xintong Dong, Yiwen Yan, Kun Yuan, Hong-Min Meng,* and Zhaohui Li*, Aptamer-Functionalized Granzyme B‑Responsive Nanoprobe for Immunotherapy Assessment: Real-Time Monitoring of Cytotoxic T Lymphocyte Activation Cleavage; Analytical Chemistry, 2025, 97, 17141−17149

Ø Bojun Liu, Di Zhao, Juan Chen, Mingqing Shi, Kun Yuan, Hongzhi Sun, Hong-Min Meng,* and Zhaohui Li*, DNA Logical Device Combining an Entropy-Driven Catalytic Amplification Strategy for the Simultaneous Detection of Exosomal Multiplex miRNAs In Situ; Analytical Chemistry, 2024, 96, 1733−1741.

Ø Juan Chen, Mingyue Xie, Mingqing Shi, Kun Yuan, Yanan Wu, Hong-Min Meng,* Lingbo Qu, and Zhaohui Li*, Spatial Confinement-Derived Double-Accelerated DNA Cascade Reaction for Ultrafast and Highly Sensitive In Situ Monitoring of Exosomal miRNA and Exosome Tracing. Analytical Chemistry, 2022, 94, 2227−2235.

Ø Yanan Wu, Zhijun Li, Mingqing Shi, Kun Yuan, Hong-Min Meng*, Lingbo Qu and Zhaohui Li*, Programmable DNAzyme Computing for Specific In Vivo Imaging: Intracellular Stimulus-Unlocked Target Sensing and Signal Amplification, Analytical Chemistry, 2021, 93, 12456−12463.

Ø Hong-Min Meng, Hui Liu, Hailan Kuai, Ruizi Peng, Liuting Mo and Xiao-Bing Zhang*. Aptamer-integrated DNA Nanostructures for Biosensing, Bioimaging and Cancer Therapy, Chemical Society Reviews, 2016, 45, 2583-2602.

奖励与荣誉（Selected honors/awards）

Ø 河南省优秀青年科学基金

Ø 河南省本科高校青年骨干教师

Ø 郑州大学学生创新创业竞赛优秀指导教师

Ø 全国大学生化学实验创新设计大赛总决赛二等奖 （第一完成人）

Ø 中国分析测试协会科学技术奖CAIA一等奖 （第三完成人）

Ø 河南省自然科学奖三等奖 （第四完成人）

Ø 河南省教育厅科技成果一等奖（第四完成人）