姜伟,男,直聘副教授,硕士生导师
地址:郑州市大学路40号郑州大学医学科学院精准医学中心实验办公室
邮箱:weijiang@zzu.edu.cn
电话:0371-61730291
邮编:450052
学习及工作经历
2019.01-至今 郑州大学 医学科学院 直聘副教授
2018.10-2018.12 郑州大学 医学科学院 讲师
2018.06-2018.10 中国科学院长春应用化学研究所 助理研究员
2015.09-2018.06 吉林大学 高分子化学与物理 攻读博士学位
2013.09-2015.06 吉林大学 高分子化学与物理 攻读硕士学位
2009.09 -2013.06 安徽师范大学 材料化学 攻读学士学位
2020年郑州大学青年骨干教师
研究方向:
? 新型绿色可控聚合制备生物医用功能高分子-纳米酶杂化材料
? 智能响应聚合物-纳米酶杂化诊疗体系构建与设计
? 基于重塑肿瘤微环境增效化疗的纳米制剂治疗耐药肿瘤
学术兼职:
Reviewer of Biomaterials and ACS Applied Materials & Interfaces
主持项目:
1. 国家科学青年基金,重塑胶质瘤微环境的新型高精准纳米诊疗体系构建与评价,81901882,2020/01-2022/12, 22万,主持
2. 中国博后面上基金,MOFs介导天然酶及纳米酶级联协同诊治帕金森的研究,2019M652583, 2019/05-2021/12,8万,主持
3. 河南省高等学校重点科研项目,高精准可视化单抗靶向型脱氧核酶传输体系的构建与评价,20A430026,2020/01 –2021/12, 3万,主持
4. 郑州大学青年教师科研启动费(拔尖博士),2018-2020,20万,主持
5. 2019 年度河南省医学科技攻关计划联合共建项目,LHGJ20190329,5万,主持
代表性文章:
#共同一作,*通讯作者
1. Chunyu Huang, Chang Zhu, Jie Chen, Kaibin Huang, Fang Li, Shunkai Ding, Ligang Xia*, Wei Jiang*, Yang Li*. Nano-platelets as an oxygen regulator for augmenting starvation therapy against hypoxic tumor. Frontiers in Bioengineering and Biotechnology. 2020. (Accepted,中科院JCR二区)
2. Daoming Zhu, Meng Lyu, Qinqin Huang, Meng Suo, Ying Liu, Wei Jiang*, Yanhong Duo*, Kelong Fan*. Stellate Plasmonic Exosomes for Penetrative Targeting Tumor NIR-II Thermoradiotherapy. ACS Applied Materials & Interfaces. 2020. (,IF=8.758,中科院JCR一区)
3. Zhu Daoming#, Lyu Meng#, Jiang Wei#, Suo Meng, Huang Qinqin, Li Kaiyang. A biomimetic nanozyme/camptothecin hybrid system for synergistically enhanced radiotherapy. J Mater Chem B. 2020, 8(24):5312-5319. (IF=5.35,中科院JCR二区)
4. Yang Yang, Daoming Zhu, Ying Liu, Bing Jiang, Wei Jiang*, Xiyun Yan*, Kekong Fan*. Platinum-Carbon Integrated Nanozyme for Enhanced Tumor Photodynamic and Photothermal Therapy. 2020, Nanoscale. (IF=6.85, 中科院JCR一区)
5. Yi Ding, Rui Wang, Lixin Dai, Haixiao Wang, Wei Jiang*, Jun Tang*, Shuang-quan Zang, Hierarchical Flower-like Mn3O4@N, P-doped Carbon Cathode for High-performance 2.6V Flexible Aqueous Asymmetric Supercapacitors. 2020, Chemical Engineering Journal. (IF=10.6 中科院JCR一区).
6. Shuiling Jin, Lanling Weng, Zhi Li, Zhenzhen Yang, Wenxue Tang, Wang Ma*, Hong Zong*, Wei Jiang*. Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy. 2020, J Mater Chem B. DOI: 10.1039/d0tb00357c. (IF=5.35, 中科院JCR二区).
7. Wei Jiang, et al. Lipase-inorganic hybrid nanoflower constructed through biomimetic mineralization: A new support for biodiesel synthesis. Journal of Colloid and Interface Science. 2018, 514, 102-107. (IF=7.489, 中科院JCR二区)
8. Wei Jiang, et al. A peroxidase mimic with atom transfer radical polymerization activity constructed through the grafting of Heme onto metal-organic frameworks. Journal of Colloid and Interface Science. 2018, 521, 62-68. (IF=7.489, 中科院JCR二区)
9. Wei Jiang, et al. Phenol degradation catalyzed by a peroxidase mimic constructed through the grafting Heme onto metal-organic frameworks. Bioresource Technology. 2018, 247, 1246-1248. (IF=7.539, 中科院JCR一区)
10. Wei Jiang, et al. Deuterohemin-peptide enzyme mimic-embedded metal-organic frameworks through biomimetic mineralization with efficient ATRP catalytic activity. ACS Applied Materials & Interfaces. 2017, 9, 26948-26957. (IF=8.758, 中科院JCR一区)
11. Jiawen Chen#, Wei Jiang#, et al. Chemoenzymatic synthesis of cholesterol-g-poly(amine-co-ester) amphiphilic copolymer as a carrier for miR-23b delivery. ACS Macro Letters. 2017, 6, 523-528. (IF=6.131,中科院JCR一区)
12. Wei Jiang, et al. One-pot combination of eROP and ROMP for the synthesis of block copolymers. MacromolecuLar Chemistry and Physics. 2015, 216, 2107-2114.(IF=2.622, 中科院JCR三区)
13. Hang Zhou, Wei Jiang, Ni An, Qiuping Zhang, Shidong Xiang, Liping Wang and Jun Tang*. Enzyme mimetic-catalyzed ATRP and its application in block copolymer synthesis combined with enzymatic ring-opening polymerization. RSC Advances. 2015, 5: 42728-42735.
14. Xing-huo Wang, Ming-xue Wu, Wei Jiang, et al. Nanoflower-shaped biocatalyst with peroxidase activity enhances the reversible addition-fragmentation chain transfer polymerization of methacrylate monomer. Macromolecules. 2018, 51, 716-723.
15. Mei Yeling, Wang Rui, Jiang Wei, et al. Recent Progress in Nanomaterials for Nucleic Acid Delivery in Cancer Immunotherapy. Biomaterials Science, 2019.
16. Zewen Zhu, Yongfei Zhang, Wei Jiang, et al. Effect of monomer sequence distribution on the CO2-philicity of a well-defined ternary copolymer: Poly(vinyl acetate-co-vinyl butyrate-co-vinyl butyl ether). Polymer. 2017, 130, 102-111.
17. Chenhui Wang, Haobo Han, Wei Jiang, et al. Immobilization of thermostable lipase QLM on core-shell structured polydopamine-coated Fe3O4 nanoparticles. Catalysts. 2017, 7(2), 49.
18. Xinghuo Wang, Wenjing Yun, Wei Jiang, et al. An amphiphilic non-viral gene vector prepared by a combination of enzymatic atom transfer radical polymerization and enzymatic ring-opening polymerization. RSC Advances. 2017, 7(16), 9926-9932.
19. Dong M, Chen J, Yang J, Wei Jiang, et al. Chemoenzymatic synthesis of cholesterol-g-poly (amine-co-ester) carrier for p53 gene delivery to inhibit the proliferation and migration of tumor cells. New Journal of Chemistry, 2018.
20. Shidong Xiang, Qiuping Zhang, Gang Zhang, Wei Jiang, et al. Facile synthesis of block copolymers by tandem ROMP and eROP from esters precursors. Biomacromolecules. 2014, 15, 3112-3118.
21. Dai L, Zhang W, Sun L, Wei Jiang, et al. Highly Stretchable and Compressible Self-healing P (AA-co-AAm)/CoCl2 Hydrogel Electrolyte for Flexible Supercapacitors. ChemElectroChem.
22. Dong M, Chen J, Yang J, Wei Jiang, et al. Chemoenzymatic synthesis of a cholesterol-g-poly (amine-co-ester) carrier for p53 gene delivery to inhibit the proliferation and migration of tumor cells. New Journal of Chemistry, 2018, 42(16): 13541-13548.
23. Yongfei Zhang, Zewen Zhu, Zhenguo Bai, Wei Jiang et al. Incorporating a silicon unit into a polyether backbone-an effective approach to enhance polyether solubility in CO2. RSC Advances. 2017. 7(27), 16616-16622.
24. Ren Hui, Xing Zhen, Yang Jiebing, Wei Jiang, et al. Construction of an immobilized thermophilic esterase on epoxy support for poly(e-caprolactone) synthesis. Molecules. 2016, 21, 796.
25. Qiuping Zhang, Qing-Lan Li, Shidong Xiang, Yan Wang, Chunyang Wang, Wei Jiang, et al. Covalent modification of graphene oxide with polynorbornene by surface-initiated ring-opening metathesis polymerization. Polymer. 2014,55: 6044-6050.
26. 姜伟, 安妮, 刘葵,汤均*. eROP结合ROMP合成嵌段聚合物PCL-b-PB-b-PCL. 吉林大学学报(理学版), 2015, 53(6):1326-1329. (EI)
27. 姜伟,李全顺*. 仿生矿化法合成次血红素六肽插入的金属有机骨架同时具有ATRP催化能力. 全国酶学学术讨论会会议论文
28. 姜伟,刘影,王星火,汤钧*. 仿生矿化法合成有机-无机杂化纳米花及其催化内酯开环聚合. 中国化学会第30届学术年会会议论文
发明专利:
1. 一种猪胰脂肪酶-无机杂化纳米花催化剂、制备方法及其在生物柴油制备中的应用(汤钧, 姜伟,丁一;授权号:CN107586770A)
2. 一种次血红素/金属有机骨架复合材料、制备方法及其在苯酚降解中的应用(汤钧,姜伟,袁博磊,黄婷婷;授权号:CN107694604A)