王利祥 博士

助理研究员

2021.12-至今     郑州大学      助理研究员

● 研究兴趣、领域：

主要研究植物次生物质与Bt毒素在害虫防治中的作用机理、农业害虫对杀虫剂的抗性机制、昆虫TRP通道功能研究、昆虫取食与产卵行为研究。

● 开设的课程：

《现代生物学原理与技术》

● 主持的项目：

1. 国家自然科学基金青年基金项目，P450介导的棉铃虫与烟青虫对烟碱耐受性差异的代谢机制，2024-2026，30万元，主持；

2. 中国博士后科学基金面上项目，P450s代谢烟碱介导的棉铃虫对烟草适应性的分子机制研究，2023-2024，8万元，主持；

3. 郑州大学博士后科学基金培育项目，植物次生物质烟碱和Bt毒素对棉铃虫的联合增效机制研究，2023-2024，10万元，主持；

4. 国家自然科学基金联合基金项目，Bt毒蛋白和植物次生物质的联合作用/交互抗性的类型及其机制，2021-2024，220万元，参与；

5. 郑州大学专职科研岗启动基金项目，2022-2023，12万元，主持；

6. 江苏省研究生培养创新工程项目，吡蚜酮影响黑腹果蝇生殖力的分子机制，2017-2018，1.5万元，主持。

● 代表性论著：

1. Lixiang Wang, Sha Tao, Yanchao Zhang, Xinguo Pei, Yang Gao, Xinyu Song, Zhitao Yu, Congfen Gao^*. Overexpression of ATP-binding cassette transporter Mdr49-like confers resistance to imidacloprid in the field populations of brown planthopper, Nilaparvata lugens. Pest Management Science, 2022.

2. Zhongyuan Deng, Yudong Ren, Lina Guo, Xingcheng Xie, Lixiang Wang, Xianchun Li^*. Genomewide analysis of G-quadruplex in Spodoptera frugiperda. International Journal of Biological Macromolecules, 2022.

3. Bin Zeng, Furong Chen, Yating Liu, Di Guo, Yi‑Jie Zhang, Zerui Feng, Lixiang Wang, John Vontas, Shunfan Wu, Kun Yan Zhu, Congfen Gao^*. A chitin synthase mutation confers widespread resistance to buprofezin, a chitin synthesis inhibitor, in the brown planthopper, Nilaparvata lugens. Journal of Pest Science, 2022.

4. Lixiang Wang, Sha Tao, Yan Zhang, Yalong Jia, Shunfan Wu^*, Congfen Gao^*. Mechanism of metabolic resistance to pymetrozine in Nilaparvata lugens: over-expression of cytochrome P450 CYP6CS1 confers pymetrozine resistance. Pest Management Science, 2021.

5. Lixiang Wang¹, Chundong Niu¹, Shunfan Wu, Congfen Gao^*. Molecular characterizations and expression profiles of transient receptor potential channels in the brown planthopper, Nilaparvata lugens. Pesticide Biochemistry and Physiology, 2021.

6. Lixiang Wang¹, Yanchao Zhang¹, Sha Tao, Di Guo, Yan Zhang, Yalong Jia, Shuai Zhang, Chen Zheng, Dilawar Khan, Congfen Gao^*, Shunfan Wu^*. Pymetrozine inhibits reproductive behavior of brown planthopper Nilaparvata lugens and fruit fly Drosophila melanogaster. Pesticide Biochemistry and Physiology, 2020.

7. Lixiang Wang¹, Chundong Niu¹, Yan Zhang, Yalong Jia, Yijie Zhang, Yue Zhang, Yuqing Zhang, Congfen Gao^*, Shunfan Wu^*. The NompC channel regulates Nilaparvata lugens proprioception and gentle-touch response. Insect Biochemistry and Molecular Biology, 2019.

8. Lixiang Wang, Chundong Niu, Salgado, V.L., Lelito, K., Stam, L., Yalong Jia, Yan Zhang, Congfen Gao^*, Shunfan Wu^*. Pymetrozine activates TRPV channels of brown planthopper Nilaparvata lugens. Pesticide Biochemistry and Physiology, 2019.

9. Qi Wei, Xichao Mu, Shunfan Wu, Lixiang Wang, Congfen Gao^*. Cross‐resistance to three phenylpyrazole insecticides and A2′ N mutation detection of GABA receptor subunit in fipronil‐resistant Laodelphax striatellus (Hemiptera: Delphacidae). Pest Management Science, 2017.

10. Shunfan Wu, Xichao Mu, Yaoxue Dong, Lixiang Wang, Qi Wei, Congfen Gao^*. Expression pattern and pharmacological characterisation of two novel alternative splice variants of the glutamate‐gated chloride channel in the small brown planthopper Laodelphax striatellus, Pest Management Science, 2017.

● 联系方式：

E-mail: wanglixiang@zzu.edu.cn; wanglixiang520nj@126.com